1. Earth Day was founded in Ohio: April 22, 1970 marks the first ever Earth Day, which was celebrated nationwide in the United States. The idea for Earth Day was first proposed by Senator Gaylord Nelson of Wisconsin, but the first major event was held in Cleveland, Ohio by environmental activist Denis Hayes.

2. Ohio State Constitution goes into effect: On April 22, 1851, Ohio adopted its state constitution, which is still in effect today. The new constitution established a bicameral legislature with a House of Representatives and a Senate, as well as a system of checks and balances.

3. Wright Brothers granted a patent: On April 22, 1902, the Wright Brothers were granted a patent for their innovative system of controlling an aircraft in flight. The patent was for a "wing warping" system that allowed pilots to adjust the angle of the wings in order to turn the plane in different directions.

4. Cincinnati Reds win first game at Riverfront Stadium: On April 22, 1970, the Cincinnati Reds won their first game at the brand new Riverfront Stadium. The stadium opened just days earlier and was the first multi-purpose stadium to be built in the United States. The Reds won the game 4-1 against the Atlanta Braves.

5. Ohio National Guard deploys to Kent State University: On April 22, 1970, Ohio Governor James Rhodes ordered the Ohio National Guard to deploy to Kent State University in response to student protests against the Vietnam War. The deployment ultimately led to the tragic shooting on May 4, 1970, where four students were killed and nine others were injured.