1. In 1901, the Indiana state legislature passed a bill to establish the Indiana University School of Medicine in Indianapolis. Today, the school is one of the largest medical schools in the United States.

2. In 1932, the Indianapolis Symphony Orchestra made its debut performance at the Murat Theatre. The distinguished orchestra has since become a beloved institution, performing over 200 concerts each year.

3. In 1973, the United States Supreme Court ruled in the landmark case Roe v. Wade that state laws banning abortions were unconstitutional. The decision would have a profound impact on reproductive healthcare in Indiana and across the country.

4. In 1999, the Indiana Fever became the 12th team to join the Women's National Basketball Association (WNBA). The team has since become a fixture of the Indianapolis sports scene, winning the WNBA championship in 2012.

5. In 2015, the Indianapolis Colts defeated the Denver Broncos 24-13 in the AFC Championship Game, earning a trip to Super Bowl XLIX. While the Colts ultimately lost to the New England Patriots in the title game, the team's playoff run offered Hoosiers a thrilling month of football.