1. The Battle of Blue Springs: On July 22, 1864, Confederate forces clashed with Union troops in the Battle of Blue Springs, which took place near Independence, Missouri. Despite being outnumbered, Union troops were able to hold their ground and force the Confederates to retreat.

2. Harry S. Truman's Birthplace: July 22 marks the birthday of former U.S. President Harry S. Truman, who was born in Lamar, Missouri in 1884. The small frame house in which he was born is now a historic site and museum.

3. Steamboat Explosion: In 1856, the steamboat Malta exploded on the Missouri River near St. Charles, killing at least 50 people. The disaster prompted calls for stricter safety regulations on steamboats.

4. Missouri Pacific Railroad Founded: On July 22, 1872, the Missouri Pacific Railroad was founded, connecting St. Louis to Kansas and the Southwest. The company was eventually absorbed into the Union Pacific Railroad in the 1980s.

5. Babe Ruth's Home Run Record: On July 22, 1920, baseball legend Babe Ruth hit his 30th home run of the season, breaking the previous record of 29 set by Ned Williamson in 1884. The home run was hit at Sportsman's Park in St. Louis, Missouri.