1. In 1869, the first train crossed the newly completed Union Pacific Railroad bridge over the North Platte River in Wyoming. This was a significant moment in the development of the Transcontinental Railroad and helped connect the eastern and western parts of the United States.

2. Wyoming became a territory on July 22, 1868, following the passage of the Organic Act by Congress. This marked an important step towards statehood for Wyoming, which would eventually become the 44th state in the Union in 1890.

3. In 1938, a massive wildfire broke out in Yellowstone National Park on July 22. This fire burned for several weeks and destroyed thousands of acres of forest and wildlife habitat. It was one of the worst wildfires in the park's history and prompted significant changes in how the park manages and prevents wildfires.

4. On July 22, 1970, the University of Wyoming was the site of a tragic shooting that claimed the lives of 14 people. The shooting was committed by a former student who was upset with the university's handling of his academic performance. This incident remains one of the deadliest school shootings in American history.

5. The Heart Mountain Relocation Center, one of ten internment camps established by the United States government during World War II, opened in Wyoming on July 22, 1942. Over 14,000 Japanese Americans were incarcerated at Heart Mountain during the war, many of whom were American citizens. The camp remains an important reminder of the injustices committed against Japanese Americans during this period.