1. In 1862, the Dakota War of 1862 began in Minnesota. This conflict between the United States government and the Dakota people lasted for six weeks and resulted in the deaths of hundreds of Dakota people and settlers.

2. In 1888, the first intercollegiate game of American football was played in Minnesota between Hamline University and Minnesota A&M. The game ended in a 0-0 tie, and it marked the beginning of a new era in American sports.

3. In 1968, the Minnesota Twins played their first game at the newly-built Metropolitan Stadium in Bloomington. The Twins won the game 5-3 against the Kansas City Royals, and the stadium would serve as the team's home until 1981.

4. In 1996, Minnesota Governor Arne Carlson signed a law that made Minnesota the first state in the United States to ban the manufacture, sale, and distribution of mercury-containing thermometers. The law was designed to protect public health and the environment from the toxic effects of mercury.

5. In 2018, Minnesota Senator Amy Klobuchar introduced the Combating the Opioid Epidemic Act, a comprehensive bill aimed at addressing the ongoing opioid crisis in the United States. The bill includes provisions for increased funding for addiction treatment and prevention programs, as well as measures to improve the monitoring of prescription drugs.