1. In 1753, the first settlers arrived at Pittsburgh, Pennsylvania. This event marked the beginning of the city's growth as a major industrial center and a hub for trade and transportation.

2. The world-renowned Hershey Chocolate Factory, located in Hershey, Pennsylvania, was founded on May 10, 1894, by Milton Hershey. The Hershey Company remains a primary employer in the region and produces some of the most popular chocolate products in the world.

3. On May 10, 1908, a deadly fire broke out at the Pennsylvania state capitol building in Harrisburg. The fire claimed the lives of six people, including two firefighters, and caused extensive damage to the historic building.

4. May 10, 1924, marked the opening day of the Grandview Golf Club in York County, Pennsylvania. The course was rated as one of the finest in the state and hosted numerous professional golf tournaments over the years.

5. The Pittsburgh Penguins won their second Stanley Cup championship in franchise history on May 10, 1992. The Penguins, led by superstar Mario Lemieux, dominated the playoffs that year and captured the title with a 6-5 victory over the Chicago Blackhawks in Game 4 of the Stanley Cup Finals.