1. Kentucky Derby: The most notable event that occurs on May 12 in Kentucky history is the annual Kentucky Derby, which is held at Churchill Downs in Louisville. The first Kentucky Derby was held on May 17, 1875, and has been run on the first Saturday in May since 1946. The race is known as the "most exciting two minutes in sports" and draws crowds from around the world.

2. Hurricane Alice: On May 12, 1954, a rare May hurricane named Alice made landfall in Kentucky. Although hurricanes are rare in the state, Alice caused widespread flooding and damage in eastern Kentucky.

3. Statehood: May 12, 1792, is the day that Kentucky officially became the 15th state in the United States. After years of being a part of Virginia, Kentucky became its own state due to its growing population and desire for more autonomy.

4. War of 1812: On May 12, 1813, General William Henry Harrison led a group of soldiers to victory against the British in the Battle of the Thames in Canada during the War of 1812. This battle is notable because it resulted in the death of British General Tecumseh, a well-known Native American leader.

5. Muhammad Ali: May 12, 1950, is the day that Muhammad Ali, one of the greatest boxers of all time, was born in Louisville, Kentucky. Ali won numerous titles throughout his career and was known for his quick wit and outspoken personality. He remains an iconic figure in both boxing and American culture.