1. The Indianapolis 500 was first held on May 30, 1911, but the race was moved to May 31 in 1912 and then to May 30 again in 1913. It wasn't until 1922 that the race was permanently scheduled for the Sunday before Memorial Day, which is typically around May 22.

2. On May 22, 1960, the first McDonald's restaurant opened in Indiana, located in Gary. This marked the beginning of a fast food dynasty that has since spread around the world.

3. The Indiana Fever of the WNBA played their first game on May 22, 2000, losing to the New York Liberty. However, the team went on to finish the season with a winning record and made the playoffs in their first year of existence.

4. The USS Indiana (BB-1), a battleship that served in both the Spanish-American War and World War I, was commissioned on May 1, 1895 and launched on May 28 of that year. The ship's first captain was Captain Thomas M. Anderson, who later became the commander of the Great White Fleet.

5. On May 22, 1819, a treaty was signed between the United States government and representatives of the Delaware, Pottawatomi, and Miami Indians, ceding a large tract of land in present-day Indiana to the US government. The treaty paved the way for further westward expansion and settlement in the state.