1. On May 22, 1846, the first telegraph line was completed in Maryland, connecting Baltimore to Washington, D.C. This historic achievement facilitated communication between the two cities and marked a significant milestone in the evolution of network communication technology.

2. In 1902, the John Hopkins University of Baltimore became the first American university to award the degree of Doctor of Science to a woman. The recipient was Gertrude Mary Cox, and this event is historically significant as it represented a major step forward for gender equality in higher education.

3. On May 22, 1939, the famous American author and poet, Stephen Crane, was posthumously awarded the Congressional Medal of Honor for his acts of bravery during the Spanish-American War of 1898. Despite being only 28 years old at the time, Crane risked his life to chronicle the experiences of American soldiers on the front lines of battle.

4. In 1965, Maryland became the first state in the U.S. to ban cigarette advertising on television and radio. This groundbreaking legislation reflected the growing public awareness of the risks associated with smoking and marked a major milestone in the effort to promote public health.

5. On May 22, 2006, the Maryland State Department of Education announced that it was partnering with Google to provide online services to schools throughout the state. This innovative program, known as Google Apps for Education, has since become one of the most widely used digital education platforms in the world.