1. On May 5, 1834, significant flooding affected Mississippi, particularly along the Mississippi River. The flood caused destruction of property and crops, as well as displacement of residents.

2. May 5, 1904, marked the opening of the Louisiana Purchase Exposition in St. Louis, Missouri. Mississippi was among the states that participated in the exposition, showcasing its agricultural and industrial products.

3. On May 5, 1964, the civil rights organization Student Nonviolent Coordinating Committee (SNCC) held a voter registration drive in Natchez, Mississippi. The drive was met with violence, as white supremacists attacked SNCC activists and African American residents.

4. In 1992, on May 5, Hurricane Andrew made landfall in Mississippi, causing significant damage to the state's Gulf Coast region. The hurricane left a path of destruction through the state, and was one of the costliest and deadliest hurricanes in U.S. history.

5. On May 5, 2012, the Mississippi State University baseball team defeated the University of Alabama in a game that lasted 26 innings, making it the longest game in Southeastern Conference history. The game lasted over seven hours and ended with a final score of 6-5 in favor of Mississippi State.