1. On November 21, 1913, the Harland Sanders Cafe and Museum, now known as the Kentucky Fried Chicken (KFC) Museum, was established in Corbin, Kentucky. The museum houses the original kitchen and dining area of Colonel Harland Sanders, the founder of KFC, and features exhibits on the history of the fast-food chain.

2. On November 21, 1898, the State Normal School (now known as Western Kentucky University) held its first classes in Bowling Green, Kentucky. The school was established to train teachers for the state's public schools and has since grown into a comprehensive university with over 20,000 students.

3. On November 21, 1871, the first issue of the Western Recorder, a Baptist newspaper, was published in Louisville, Kentucky. The paper has since become a leading religious newspaper in the region, covering Baptist news and events.

4. On November 21, 1938, the state of Kentucky adopted its first constitution under its current name, the Commonwealth of Kentucky. The constitution established the state's legislative, executive, and judicial branches of government and has since undergone several revisions.

5. On November 21, 1967, the Marshall University football team, along with several fans and coaching staff, died in a plane crash while returning from a game in North Carolina. The tragedy, known as the Marshall University plane crash, remains one of the deadliest disasters in American sports history and is commemorated annually by the university and its fans.