1. On November 21, 1836, Juan Seguin was elected as the first senator to represent Bexar County in the Republic of Texas Senate. Seguin had previously served as a captain in the Texas Revolution and was a key figure in the Battle of San Jacinto.

2. On November 21, 1963, President John F. Kennedy visited San Antonio, Texas as part of a two-day tour of the state. It would be his last visit to Texas before his assassination in Dallas just two days later.

3. On November 21, 1969, the Texas A&M University Bonfire collapsed during construction, killing 12 people and injuring 27 others. The tragedy led to the end of the Bonfire tradition and a period of mourning for the university.

4. On November 21, 1980, the deadliest hull-loss accident in aviation history occurred when a chartered plane carrying 87 passengers, including 10 members of the Texas-based rock band, Lynyrd Skynyrd, crashed in Mississippi. There were 26 fatalities, including several band members.

5. On November 21, 2016, a wildfire swept through the small town of Tahoka, Texas, destroying several homes and businesses. The fire was caused by high winds and dry conditions, and it burned over 3,000 acres of land. The town was able to rebuild and recover from the devastation.