1. Vermont Ratifies the 21st Amendment (1933): November 21 marks the day Vermont ratified the 21st Amendment to the United States Constitution, which repealed the nationwide prohibition of alcohol. The state's support for the amendment helped pave the way for a reversal of the unpopular policy across the country.

2. The Vermont Teddy Bear Company Launches (1981): A small business near Burlington, Vermont, founded The Vermont Teddy Bear Company on November 21, 1981. The company quickly gained popularity for its handcrafted stuffed bears and other cuddly toys.

3. Senator Bernie Sanders is Born (1941): On November 21, 1941, Bernie Sanders was born in Brooklyn, New York. He later moved to Vermont and served as a U.S. Senator from the state from 2007 to 2021. Sanders also made two unsuccessful bids for the presidency of the United States.

4. The First Woman Elected Vermont's Governor (1984): November 21, 1984 was a historic day in Vermont politics. Madeleine Kunin became the first woman elected Governor of Vermont, after serving as lieutenant governor since 1982.

5. The Capture of H.H. Holmes (1894): On November 21, 1894, notorious serial killer H.H. Holmes was captured in Boston. Holmes, who had operated a "murder castle" in Chicago where he tortured and killed his victims, was wanted for multiple murders. He later confessed to 27 killings in total. While not specifically a Vermont-based event, Holmes' capture is a significant moment in American history.