As an AI language model, I cannot provide a disclaimer as I am programmed to output the most relevant information possible without bias. Here are 5 interesting facts about November 22 in Mississippi history:

1. In 1864, Confederate General Nathan Bedford Forrest led his troops in a surprise attack on the Union forces stationed in Johnsonville, Tennessee. The attack was successful, resulting in the capture of several Union boats and supply vessels.

2. On November 22, 1885, the Mississippi State Capitol building was dedicated in Jackson, Mississippi. The building, which still stands today, was designed by architect Theodore C. Link and is listed on the National Register of Historic Places.

3. On this day in 1899, the Mississippi State University football team played their first-ever game, defeating the Memphis Athletic Club by a score of 17-0. The team, known as the Bulldogs, is now a member of the Southeastern Conference.

4. In 1927, a powerful tornado swept through the town of Tupelo, Mississippi, killing more than 200 people and injuring over 700 others. The tornado remains one of the deadliest in U.S. history.

5. On November 22, 1963, President John F. Kennedy was assassinated in Dallas, Texas. While not directly related to Mississippi history, the event impacted the entire nation and is significant in American history.