1. On November 22, 1963, President John F. Kennedy was assassinated in Dallas, Texas. While this event did not take place in Mississippi, it had a profound impact on the state and the nation as a whole.

2. On November 22, 1903, the Mississippi State Penitentiary, also known as Parchman Farm, admitted its first prisoners. The prison would go on to become notorious for its harsh conditions and use of convict labor.

3. November 22, 1954, saw the brutal murder of civil rights activist Lamar Smith in Brookhaven, Mississippi. Smith had been organizing voter registration drives in the area, and his death was a stark reminder of the dangers faced by those fighting for racial equality in the South.

4. On November 22, 2014, the Mississippi State Bulldogs football team beat the Vanderbilt Commodores 51-0. The win extended the team's record to 9-2 and kept alive their hopes of a berth in the College Football Playoff.

5. November 22, 1965, was the birthdate of actress Salli Richardson-Whitfield, who grew up in Chicago but spent part of her youth in Jackson, Mississippi. Richardson-Whitfield has appeared in numerous films and television shows, including "Eureka" and "The Newsroom."