1. On November 4, 1820, the Missouri Compromise was passed by Congress, allowing Missouri to enter the Union as a slave state while Maine entered as a free state, thus maintaining the balance between free and slave states in the US.

2. On November 4, 1839, the state of Missouri chartered the St. Louis University, a private Jesuit research university in St. Louis, Missouri, which is still in operation today.

3. On November 4, 1899, the Battle of Manila Bay took place during the Philippine-American War, in which the US Navy defeated the Spanish Navy, leading to the US occupation of the Philippines and the eventual colonization of the country by the United States.

4. On November 4, 1922, the Lincoln Theatre, a popular entertainment venue for African Americans during the segregation era, opened in Kansas City, Missouri, and quickly became one of the most important theaters in the Midwest.

5. On November 4, 2014, Missouri became the first state in the US to legalize medical marijuana through a ballot measure, with voters approving Amendment 2, which allows patients with certain medical conditions to use cannabis products for medical purposes.