1. The first transcontinental airmail service in the United States began on October 21, 1926, with a flight from New York to San Francisco, which included a stop in Michigan. The airmail service was an important milestone in the development of commercial aviation.

2. On October 21, 1915, the Michigan State Capitol Building was dedicated in Lansing. The building was designed in the neoclassical style and is one of the most impressive capitol buildings in the country.

3. The Michigan Wolverines football team played their first game on October 21, 1879, against Racine College. The Wolverines won the game 1-0 and went on to become one of the most successful college football programs in history.

4. The Mackinac Bridge, which connects Michigan's Upper and Lower Peninsulas, was officially opened on October 21, 1957. The bridge is the longest suspension bridge in the Western Hemisphere and is a major landmark in the state of Michigan.

5. On October 21, 1861, Michigan Senator Zachariah Chandler introduced a bill in Congress that would establish the first land-grant college in the United States. The bill was eventually signed into law by President Abraham Lincoln and led to the creation of Michigan State University.