1. In 1792, North Carolina ratified the United States Constitution, becoming the 12th state to do so. The state had originally refused to ratify the Constitution until the Bill of Rights was added. This event is celebrated annually as "Statehood Day."

2. On October 22, 1900, the first streetcar line was established in Charlotte, North Carolina. The line ran from downtown Charlotte to Myers Park and was operated by the Charlotte Consolidated Construction Company.

3. In 1953, the University of North Carolina at Chapel Hill officially desegregated, allowing Black students to enroll for the first time. The university had previously been all-white, and the decision to desegregate was met with resistance from some members of the community.

4. On October 22, 1977, artist Andrew Wyeth unveiled his painting "First Love" at the North Carolina Museum of Art in Raleigh. The painting depicts a young girl standing in a barn and became one of Wyeth's most popular works.

5. In 2009, North Carolina became the first state in the country to establish a state-level Veterans Treatment Court. The court is designed to provide an alternative to traditional criminal court proceedings for veterans who suffer from substance abuse or mental health issues related to their service.