1. In 1851, the first issue of The Milwaukee Daily Sentinel was published. It was a prominent newspaper in Milwaukee that covered local and national news.

2. On September 18, 1854, the Milwaukee and Mississippi Railroad was completed, linking Milwaukee to the Mississippi River and providing a crucial transportation route for agriculture and industry.

3. In 1923, the Wisconsin Gas Company opened a gas-fired power station on Milwaukee's Jones Island, the first such plant in Wisconsin. This helped provide electricity to the growing city and region.

4. The Wisconsin Badgers football team played their first ever night game on September 18, 1959, defeating the Washington Huskies 44-8. Night games have since become a staple of college football.

5. Milwaukee-born artist Mark Waldoch won the first ever Milwaukee Film Festival Poster Contest on September 18, 2008. His winning design depicted a film reel shaped like Milwaukee's iconic Calatrava Art Museum.