1. On September 22, 1867, the U.S. flag was raised for the first time in Sitka, Alaska, signifying the transfer of Alaska from Russia to the United States. This event is now celebrated annually as Alaska Day.

2. In 1909, on September 22, the first airplane flight in Alaska was conducted by James V. Martin in Fairbanks. Martin flew a biplane that he had built himself, and his flight marked the beginning of aviation in the Last Frontier.

3. On September 22, 1964, a powerful earthquake struck Alaska, measuring 9.2 on the Richter scale. Known as the Great Alaska Earthquake, it is the largest earthquake ever recorded in North America and the second-largest earthquake in recorded history.

4. In 1980, on September 22, the Alaska National Interest Lands Conservation Act (ANILCA) was signed into law by President Jimmy Carter. This legislation designated over 104 million acres of land in Alaska as national parks, wildlife refuges, and wilderness areas.

5. On September 22, 1994, the Alaska Native Claims Settlement Act (ANCSA) was amended to allow for the creation of regional corporations. These corporations were established to manage and develop the lands and resources granted to Alaska Native people under ANCSA, and they continue to play a significant role in Alaska's economic and social landscape.