1. Iowa State Fair: On September 22, 1868, the first Iowa State Fair was held in Des Moines. It is now one of the largest state fairs in the United States, attracting more than one million visitors annually.

2. Tornado Outbreak: On September 22, 2006, a tornado outbreak hit eastern Iowa, causing significant damage in the towns of Vinton and Cedar Rapids. The tornado caused millions of dollars in damages and injuries to dozens of people.

3. Black Hawk: On September 22, 1804, the legendary Sauk leader Black Hawk was born in present-day Illinois. He would later lead a resistance against the United States government, known as the Black Hawk War, which ended in defeat at the Battle of Bad Axe in Wisconsin.

4. State Bird: On September 22, 1933, the Eastern Goldfinch was designated as the official state bird of Iowa. Also known as the American Goldfinch, it is found throughout North America and is known for its vibrant yellow plumage.

5. Cyclone Football: On September 22, 1979, the Iowa State Cyclones defeated the Nebraska Cornhuskers in Lincoln, Nebraska, by a score of 21-17. The victory was Iowa State's first over Nebraska in 23 years and is often cited as one of the greatest upsets in college football history.