1. The Little Rock Nine were escorted into Little Rock Central High School on September 25, 1957. This event marked a significant moment in the Civil Rights Movement, as these nine African American students were the first to integrate into the previously all-white school.

2. On September 25, 1863, Confederate troops under General Sterling Price engaged in the Battle of Saint John's Bluff near Jacksonville, Florida. Despite heavy losses on both sides, the Confederates were ultimately forced to retreat.

3. On September 25, 1903, the Arkansas State Fair opened for the first time in Hot Springs. Since then, the fair has become one of the largest annual events in the state, drawing visitors from all over.

4. Arkansas-born author William Least Heat-Moon was born on September 25, 1939 in Kansas City, Missouri. Heat-Moon is best known for his travel writing, including his book "Blue Highways," which chronicled his journey across America on backroads.

5. On September 25, 1854, the Fayetteville Female Seminary officially opened its doors, offering higher education to women. The school later became the University of Arkansas and is now a prominent research institution.