1. The Ohio State University was founded on February 21, 1870. The university is now one of the largest universities in the United States with over 68,000 students enrolled across its campuses.

2. On February 21, 1965, Malcolm X delivered his famous speech in Cleveland, Ohio titled "Not just an American problem, but a world problem". The speech addressed the need for unity among people of color and the significant issues they faced.

3. Aviation pioneer Glenn Curtiss was born on February 21, 1878, in Hammondsport, New York. He owned a factory in Columbus, Ohio where he produced hundreds of airplanes during World War I.

4. The NBA's Cleveland Cavaliers set a franchise record on February 21, 1994, by scoring 195 points in a game against the Denver Nuggets. The game ended in a 148-147 victory for the Cavs in one of the highest-scoring games in NBA history.

5. On February 21, 1952, Akron, Ohio became the first U.S. city to use fluoridation for its water supply. Fluoridation is a process where fluoride is added to a community's water supply to prevent tooth decay. Today, the practice is used by many communities across the United States.