1. On February 22, 1787, the Ohio General Assembly passed a law establishing Ohio University, making it the first institution of higher learning in the Northwest Territory.

2. In 1861, on February 22, Jefferson Davis was inaugurated as the President of the Confederate States of America. This eventually led to Ohio and other northern states supporting the Union in the Civil War.

3. On February 22, 1897, Ransom E. Olds, an Ohio native, founded the Olds Motor Vehicle Company, one of the pioneering auto manufacturers in the United States. Olds later went on to found the REO Motor Car Company.

4. In 1935, on February 22, the Ohio River flooded, causing extensive damage throughout the state. The flooding also prompted the construction of new flood control measures, including dams and levees.

5. On February 22, 1980, the United States Olympic hockey team, which included Ohio native Mark Wells, defeated the Soviet Union in the "Miracle on Ice" game at the Winter Olympics in Lake Placid, New York. The victory is considered one of the greatest upsets in sports history.