1. On March 22, 1622, Native Americans attacked English settlements in Virginia in what became known as the Jamestown massacre. Over 300 settlers were killed, marking a turning point in relations between the English and Native American tribes.

2. The first recorded intercollegiate baseball game in the United States was played on March 22, 1873, between Amherst College and Williams College in Richmond, Virginia. Amherst won the game 73-32.

3. On March 22, 1900, the Virginia General Assembly passed the Racial Integrity Act, which categorized individuals as either "white" or "colored" based on their ancestry. The law would remain in effect until being overturned by the Supreme Court in 1967.

4. Virginia native Patsy Cline, one of the most influential and successful female country music singers of all time, was born on March 22, 1932, in Winchester. Cline's hits include "Crazy," "Walkin' After Midnight," and "I Fall to Pieces."

5. On March 22, 1975, Virginia became the first state in the nation to enact a mandatory seat belt law, requiring drivers and front-seat passengers to wear seat belts while operating a vehicle. The law would later be adopted by every state in the U.S.