1. In 1859, the Comstock Lode, one of the largest silver mines in the world, was discovered in what is now Virginia City, Nevada. The discovery changed the economic and social landscape of Nevada, and attracted thousands of prospectors and miners to the area.

2. On May 21, 1900, the state of Nevada officially adopted the sagebrush as its state flower. The sagebrush, also known as the Artemisia tridentata, is a hardy plant that is native to the western United States.

3. On May 21, 1927, Charles Lindbergh made a stop in Las Vegas during his historic solo flight across the Atlantic Ocean. Lindbergh's flight captured the attention of the world, and his visit to Las Vegas was seen as a major event for the city.

4. In 1973, the MGM Grand Hotel and Casino (now Bally's Las Vegas) opened on the Las Vegas Strip. At the time, it was the largest hotel in the world, with over 2,000 rooms. The hotel has since undergone several renovations and name changes, but remains a popular destination for visitors to Las Vegas.

5. On May 21, 2014, a major wildfire broke out in the northern part of the state, near the town of Elko. The fire, known as the Martin Fire, eventually burned over 400 square miles of land and destroyed several homes and buildings. It was one of the largest wildfires in Nevada's history, and required a massive response from firefighters and other emergency responders.