1. The first train arrived in Reno on May 22, 1872. It marked a significant moment in the state's development as transportation links helped to connect communities and boost the economy.

2. On May 22, 1908, a huge fire broke out in the timber mill town of Loyalton, destroying almost the entire town. The disaster led to the creation of a more professional firefighting service in Nevada.

3. May 22, 1911 was the day that the state's first-ever airfield opened in Reno. The facility helped to foster aviation innovation in the state, and set the stage for subsequent aviation and aerospace developments.

4. On May 22, 1958, the first working model of the atomic clock was unveiled at the National Bureau of Standards in Washington, D.C. Although not strictly a Nevada event, the clock's precise time-keeping capabilities revolutionized the measurement of time and had a global impact.

5. Finally, May 22, 2000 marked the opening of the Palms Casino Resort in Las Vegas. The venue was designed to cater to a more sophisticated clientele than traditional casinos and became known for its upscale amenities and exclusive celebrity events.