1. The first public school in New Hampshire was founded on September 22, 1635, in what is now the town of Portsmouth. The school was established by Reverend William Hilton and provided education to the children of the colonists.

2. On September 22, 1862, the Battle of Antietam took place in Maryland during the American Civil War. Many soldiers from New Hampshire fought in this battle, including the 5th and 6th New Hampshire Infantry regiments. The battle remains the bloodiest single-day battle in American history.

3. On September 22, 1918, a massive forest fire broke out in the White Mountains of New Hampshire. The fire destroyed over 50,000 acres and led to the deaths of at least 45 people. The fires were caused by sparks from locomotives used to transport logs.

4. The New Hampshire State House was first opened on September 22, 1819. The building is located in Concord and is the oldest state capitol building in the country that has continuously housed state government.

5. On September 22, 1789, George Washington visited Portsmouth, New Hampshire, on his tour of the New England states. He was greeted by a large crowd of residents and visited several homes and public buildings in the city.