1. On September 27, 1839, the Ohio State Board of Agriculture was established. It was the first state agriculture board formed in the United States and paved the way for the modernization of Ohio's agricultural industry.

2. In 1903, the Dayton-Wright Company was founded in Dayton, Ohio. The company went on to become a leading manufacturer of aircraft during World War I and played a significant role in the development of early aviation technology.

3. September 27, 1872, marked the opening of the first public library in the city of Cincinnati. The library was originally located in a rented room and soon outgrew its space, prompting the construction of a new, larger facility.

4. In 1958, the Cleveland Browns football team played their first game in the newly constructed Cleveland Municipal Stadium. The stadium, which could seat over 80,000 people, was a landmark of Cleveland sports for over 50 years.

5. September 27, 1909, saw the birth of James M. Cox, who would go on to serve as the Governor of Ohio and run for President of the United States in 1920. Cox was also the founder of the Dayton Daily News and a prominent statesman and philanthropist in Ohio.